New Monkeypox CPT Codes Released for Testing and Vaccination

New Monkeypox CPT Codes Released for Testing and Vaccination

The American Medical Association (AMA) has developed and released new monkeypox CPT codes from the regular schedule to address a public health concern and track and report monkeypox testing and vaccinations. The Centers for Disease Control and Prevention (CDC) is tracking over 17,000 confirmed cases of monkeypox in 69 non-endemic countries, territories, and areas that don’t normally report this condition. CDC encourages those who have been exposed to monkeypox and people who may be more likely to get monkeypox to get vaccinated.

monkeypox cpt codes

According to CDC, those more likely to get monkeypox include people:

  • Identified by public health officials as a contact of someone with monkeypox
  • With sexual partners in the past two weeks diagnosed with monkeypox
  • With multiple sexual partners in the past two weeks in an area with known monkeypox
  • With jobs in which they may be exposed to orthopoxviruses such as:
    • Laboratory workers performing testing or handling cultures or animals with orthopoxviruses
    • Some designated healthcare or public health workers

The CDC website provides more details on the monkeypox disease, treatment, and vaccination.

What are the Monkeypox CPT Codes for Testing and Vaccination?

The following monkeypox CPT codes for testing and vaccination have been developed and released by the AMA:

Laboratory Test Code

87593Infectious agent detection by nucleic acid (DNA or RNA); orthopoxvirus (e.g., monkeypox virus, cowpox virus, vaccinia virus), amplified probe technique, eachDescribes molecular diagnostic testing that detects the nucleic signature of an orthopoxvirus, including the monkeypox virus

Vaccine Product Codes

90622Vaccinia (smallpox) virus vaccine, live, lyophilized, 0.3 mL dosage, for percutaneous useDescribes the existing FDA-approved ACAM2000 vaccine manufactured by Sanofi Pastuer Biologics Co. for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection
90611Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative-free, 0.5 mL dosage, suspension, for subcutaneous useDescribes the FDA-approved JYNNEOS vaccine manufactured by Bavarian Nordic for prevention of smallpox and monkeypox disease in adults 18 years of age and older at high risk for smallpox or monkeypox infection

For information on the ICD-10-CM code for monkeypox, please see our previous article, “Monkeypox: Disease Breakdown & Diagnosis Code for Monkeypox Virus.”

Ann Zeisset

Ann Zeisset, RHIT, CCS, CCS-P Contract Educator
monkeypox cpt codes

Subscribe to our Newsletter


  • By clicking Submit, you agree to YES HIM Consulting's Privacy Policy and Terms of Use.